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5 Amino 1MQ

$22.99

5‑Amino‑1‑Methylquinolinium (5‑Amino‑1MQ) is a synthetic quaternary ammonium analogue that selectively inhibits nicotinamide N‑methyltransferase (NNMT), elevating intracellular NAD⁺ and modulating methylation flux. In cellular systems, it serves as a key reagent for studies of NNMT activity, NAD⁺‑dependent pathways, and SAM‑mediated methylation dynamics. 5‑Amino‑1MQ is ideal for in vitro assays, animal studies, and cell‑culture experiments investigating enzyme kinetics, metabolic regulation, or epigenetic methylation.

≥98% Purity · HPLC VerifiedLab Tested · View COA →
The Front Range Quality Promise · see what’s covered →

+ Orders over $200 include a free 10ml BAC water.

BULK PRICING (per product)applied automatically at cart — no code needed
10–19 vials: 10% off · 20–39: 20% · 40–69: 30% · 70+: 40%

5‑Amino‑1‑Methylquinolinium (5‑Amino‑1MQ) is a synthetic quaternary ammonium analogue of naturally occurring methylquinolinium, designed to selectively inhibit cytosolic nicotinamide N‑methyltransferase (NNMT). NNMT catalyzes the transfer of a methyl group from S‑adenosyl‑L‑methionine (SAM) to nicotinamide and related substrates; by competing with nicotinamide for NNMT binding, 5‑Amino‑1MQ elevates intracellular NAD⁺ levels and alters methylation flux, making it a key reagent for studies of methyltransferase regulation and cellular energy homeostasis.

Note: 5 Amino 1MQ is intended for research purposes only and is not approved for human consumption. All products are shipped in lyophilized form and must be reconstituted to a liquid for research and testing. We are unable to provide any dosing instructions. All products should be considered pharmaceutical grade.

Weight .2 lbs
size

5mg

Is this for human or animal use?
No. Front Range products are research peptides intended for laboratory research purposes only. They are not for human or animal consumption.
Is the purity tested? How?
Yes. Every batch is tested by HPLC for identity and purity. Standard target: ≥98% purity. Specific purity per batch is shown on each product’s COA.
Where can I find the COA?
Click “View COA” near the Add to Cart button. Each product has a COA from third-party HPLC testing.
How should this be stored?
Lyophilized (powder) form: freezer at −20°C for long-term, or fridge (2–8°C) for short-term. Once reconstituted: refrigerate (2–8°C), use within 30–60 days depending on the peptide. Avoid freeze-thaw cycles. Keep out of direct sunlight.
What’s the shelf life?
Lyophilized: 24+ months at −20°C. Reconstituted: 30–60 days refrigerated, depending on the specific peptide.
How fast do you ship?
Same-day shipping when ordered by 2pm Central Time, Monday–Friday. Live UPS rates at checkout.
When is shipping free?
Free shipping on orders over $175.
What payment methods do you accept?
Credit/Debit Cards and ACH/eCheck via Plaid. Universities and institutions: we can usually arrange purchase orders or invoiced payments — just reach out.
What’s your return policy?
If your order arrives damaged, contact us — we replace it free. Otherwise, due to the nature of research compounds, we don’t accept returns once shipped. Reach out if anything’s wrong; we’ll make it right.
What if my order arrives damaged?
Email us a photo of the damaged item within 7 days of delivery. We’ll replace it at no charge.
Are these products legal?
Research peptides sold for laboratory research purposes are legal in the United States. They are not approved by the FDA for human or animal use. Front Range Aminos operates lawfully under research-supply standards.
Where are you based?
Front Range, Colorado. Family-owned and operated. We pack and ship every order ourselves.
Do you offer institutional or academic accounts?
Yes. Universities, labs, and research institutions can request invoice billing, purchase orders, or bulk pricing. Contact us with your account needs.
How are products shipped — temperature-sensitive?
Front Range peptides are stable in lyophilized form for shipping. Cold-chain is not required.
Do you ship internationally?
We ship within the United States only (contiguous 48, Alaska, and Hawaii).
What does “research peptide” mean?
Research peptides are short chains of amino acids used in scientific and laboratory research to study biological pathways, receptor interactions, and cellular processes. They are not therapeutic products.
What is 5-Amino-1MQ commonly studied for?
A small-molecule NNMT (nicotinamide N-methyltransferase) inhibitor studied in research examining NAD+ salvage pathway preservation and adipocyte metabolism.

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